What is Zopiclone?
Zopiclone uk is a medication prescribed for the treatment of Insomnia, a common sleep disorder. It is classified as a non-benzodiazepine hypnotic, distinguishing it from benzodiazepine sedative hypnotics like Halcion (triazolam), although it shares similar effects and potential side effects.
This medication aids in reducing the time required to fall asleep (sleep latency), prolonging total sleep time (sleep duration), and minimizing nighttime awakenings (nocturnal awakenings). Zopiclone typically begins to take effect within approximately one hour.
The mechanism of action for zopiclone / sleeping pills involves its binding to the gamma-aminobutyric acid type A (GABAA) receptor in the brain, which enhances the effects of gamma-aminobutyric acid (GABA), a neurotransmitter known for its calming properties.
Zopiclone was introduced in the 1980s and is authorized for use in various regions worldwide. However, it is not available in the United States, where it is classified as a Schedule IV controlled substance. The U.S. Food and Drug Administration (FDA) has approved eszopiclone (Lunesta), a stereoisomer of zopiclone, which consists of the same components arranged in a different three-dimensional structure.
Typically, zopiclone is available in tablet form. In certain countries, physicians may prescribe an oral solution of this medication for patients who have difficulty swallowing. Both branded and generic formulations of zopiclone can be found in the market.
What is zopiclone used for?
Zopiclone is prescribed for the short-term management of insomnia in adults, typically lasting between 7 to 14 days. It addresses various sleep-related issues, including:
- Difficulty initiating sleep
- Frequent awakenings during the night
- Early morning awakenings
- Significant sleep disturbances linked to mood or mental health conditions
The use of Zopiclone 10mg uk for chronic insomnia is not advised for periods exceeding four weeks, as it may lead to tolerance and dependence. Discontinuing the medication abruptly can result in withdrawal symptoms and rebound insomnia. Prolonged use is generally regarded as an “off-label” application of the medication.
Important information
Zopiclone may cause serious side effects.
The use of this medication may result in the potential for abuse and/or the development of both physical and psychological dependence. The likelihood of dependence escalates with increased dosage and prolonged treatment duration, particularly when the medication is administered for over four weeks, or in individuals with a history of mental health issues and/or substance abuse involving alcohol or illicit drugs.
The combination of zopiclone with opioids can lead to severe side effects, including drowsiness, respiratory difficulties, coma, and even death. Concurrent use of zopiclone and opioids should be limited to situations where alternative treatments are insufficient. It is essential to inform your doctor about all opioid medications you are currently taking and to adhere strictly to their prescribed dosage.
Research has indicated a heightened risk of suicidal thoughts, suicide attempts, and suicide among patients using certain sedatives and hypnotics, including this medication. However, it remains unclear whether this association is directly linked to the medication or if other factors are involved. If you experience any suicidal thoughts, it is crucial to seek medical advice from your doctor promptly.
Prior to initiating treatment with zopiclone, ensure that you can secure a minimum of 7 to 8 hours of uninterrupted sleep, as this may help mitigate the risk of certain side effects.
Zopiclone 7.5mg has the potential to induce sleepwalking or other atypical behaviors (such as driving, eating, making phone calls, or engaging in sexual activities) while the individual is not fully awake. You may not recall these actions the following morning. Such behaviors can occur regardless of alcohol consumption or the use of other sedative medications alongside zopiclone. Should you encounter any of these incidents, discontinue the medication immediately and consult your doctor or healthcare provider.
Who should not take zopiclone?
You should not use zopiclone if you have any of the following conditions:
– An allergy (hypersensitivity) to zopiclone uk or any of its components. Symptoms of an allergic reaction may include a rash, difficulty swallowing or breathing, and swelling of the lips, face, throat, or tongue.
– A condition that leads to significant muscle weakness, such as myasthenia gravis.
– Impaired lung function, known as respiratory failure.
– A disorder characterized by temporary cessation of breathing during sleep, referred to as sleep apnea.
– Severe liver dysfunction. – You are under 18 years of age, as the safety and effectiveness of zopiclone have not been determined for children and adolescents in this age group.
– A history of sleepwalking or other atypical behaviors (such as driving, eating, making phone calls, or engaging in sexual activity) while not fully awake after taking zopiclone.
What should I tell my doctor before taking zopiclone?
Prior to using zopiclone tablets in UK, it is essential to inform your healthcare provider about all your medical conditions, particularly if you:
- are experiencing any liver issues, as your physician may need to prescribe a reduced dosage of zopiclone.
- have any kidney concerns, which may also necessitate a lower dose of zopiclone from your doctor.
- have mild respiratory difficulties; your physician will assess whether zopiclone is appropriate for you.
- have a history of mental health disorders, such as depression or personality disorders, or if you have a history of substance abuse or dependence on alcohol or drugs.
- have recently used zopiclone or similar medications for a duration exceeding four weeks.
- are currently taking opioid medications.
What are the side effects of zopiclone?
- Allergic reactions. The signs of an allergic reaction may include:
o a rash
o swallowing or breathing problems
o swelling of your lips, face, throat or tongue
- Stop taking this medication and see a doctor or go to the emergency room straight away if you develop symptoms of an allergic reaction.
- Tell your doctor as soon as possible if you have any of the following side effects, which are rare or of unknown frequency:
- Poor memory (amnesia) since starting this medication. This problem is less likely to occur if you have 7-8 hours of uninterrupted sleep after taking this medication.
- Seeing or hearing things that are not real (hallucinations)
- Falling, especially in the elderly
- Thinking things that are not true (delusions)
- Feeling low or sad (depressed mood)